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BIOANALYSIS Clinical Lab

Getting tested and treated for sexually transmitted infections (STIs) is straightforward and confidential

 

Sexually transmitted diseases (STDs) are among the most common infections with clinical characterization being in many cases difficult as they can be asymptomatic but also their isolation using standard methods difficult. Since untreated infections with these pathogens can in time lead to serious consequences, PCR analysis can unveil with high sensitivity and specificity the cause of an infection.

There are over 30 different sexual transmitted bacteria, viruses and parasites therefore a screening panel might be recommended. Eight of these pathogens are linked to the greatest incidence of sexually transmitted disease of whcich 4 are currently curable: syphilis, gonorrhoea, chlamydia and trichomoniasis.

The other 4 are viral infections which are incurable but require imidiate addention: hepatitis B, herpes simplex virus (HSV or herpes), HIV and human papillomavirus (HPV).


 

 

HPV Panels

The human papillomavirus (HPV) is the etiological factor for more than 99% of cervical cancers worldwide,  and has over 200 genotypes, some of which are spread through sexual intercourse. Sexually transmitted HPV types fall into two groups, low risk and high risk. Low-risk HPVs mostly cause no disease while certain types of HPV that includs types 16 and 18 are considered high risk as they increase risk to develop cervical cancer.

PCR screening can identify HPV at early stages. As this virus can put you at high risk of cervical cancer, early detection can allow you and your doctor to respond fast.

Close monitoring can prognose cervical changes that lead to cancer that usually takes several years — often 10 years or more — to develop. For these reasons, you might follow a course of watchful waiting instead of undergoing treatment immediately.

There are several assays to choose from, such as screening for high risk types to performing genotyping HPV analysis.


 

Standard HPV Panel by RT-PCR Analysis:

 

High Risk genotypes 16 and 18 and screening for 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68 


 

Extended HPV Panel by RT-PCR Melting Curve Analysis for 40 Genotypes:

 

High-risk genotypes (20 genotypes) 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 69, 70, 73, and 82

Low-risk genotypes (2 genotypes) 6 and 11

Other genotypes (detection only, 18 genotypes) 30, 32, 34, 40, 42, 43, 44, 54, 55, 61, 62, 67, 74, 81, 83, 84, 87,and 90

Specimen type:  Female - Vaginalswab 

Male - Urine or Urethral Swab

 

Sexual Transmitted disease panels:

Sexual transmitted infections (STIs) represents a group of diseases that affect the sexual and reproductive health caused  by different etiological agents fungi, bacteria, parasites and viruses.

A molecular PCR test has been developed to achieve the highest sensitivity and specificity for the intended target DNA that aim to aid in the diagnosis of STDs.

Our panel, using a single multiplex PCR assay identifies and differentiates seven common STI bacteria such as Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Trichomonas vaginalis, Ureaplasma urealyticum, Ureaplasma parvum and Mycoplasma hominis, in clinical samples from patients with signs and symptoms of STDs.

While the extended panel includes also Haemophilus ducreyi, Gardnerella vaginalis, Candida albicans (common yeast infection), Treponema pallidum and Genital herpes virus (HSV 1 & 2).

 

Standard STD Panel by RT-PCR Analysis:

  1. Chlamydia trachomatis
  2. Ureaplasma parvum
  3. Trichomonas vaginalis
  4. Mycoplasma genitalium
  5. Mycoplasma hominis
  6. Neisseria gonorrhoeae
  7. Ureaplasma urealyticum              

 

 

 

Extended STD Panel by RT-PCR Melting Curve Analysis:

  1. Chlamydia trachomatis
  2. Ureaplasma parvum
  3. Trichomonas vaginalis
  4. Mycoplasma genitalium
  5. Mycoplasma hominis
  6. Neisseria gonorrhoeae
  7. Ureaplasma urealyticum
  8. Haemophilus ducreyi
  9. Gardnerella vaginalis
  10. Candida albicans
  11. Treponema pallidum
  12. Herpes simplex virus 1
  13. Herpes simplex virus 2

Specimen Type :

 

Female -Vaginalswab sample

Male - Urine /Urethral swab sample